珞珈讲坛第282讲
时 间：2019年1月6 日（周日）10:00
地 点：武汉大学樱顶老图书馆
主讲人：谭建荣教授 中国工程院院士
题 目：人工智能与智能制造：关键技术与发展趋势
主讲人简介：
谭建荣，浙江湖州人，中国工程院院士，国家973项目首席科学家，浙江大学求是特聘教授，博士生导师，担任浙江大学设计工程及自动化系主任，浙江大学机器人研究院名义院长，中国大数据技术与应用产业联盟理事长，中国机械工程学会副理事长，中国图学学会副理事长，教育部工程图学教学指导委员会主任，先后获“科技部十五863先进个人”、“科技部十一五国家科技计划执行突出贡献奖”、‘‘全国优秀科技工作者’’等荣誉和称号。
主要从事数据建模与虚拟现实，数字设计与智能製造方面的研究，获国家科技进步二等奖4项，省部级科技进步一等奖7项，教学成果获国家级优秀教学成果奖3项，其中一等奖1项，二等奖2项。获发明专利和软件著作登记权56项。
Brief Introduction of Professor Jianrong Tan
Jianrong Tan,from Huzhou,Zhejiang，is an academician of Chinese Academy of Engineering, Ministry of science and technology "973" project Chief Scientist, “Qiu Shi”special professor and Ph.D. supervisor of Zhejiang University.Working as Director of department design engineering and automation , the dean of the Institute of Robotics of Zhejiang University, Chairman of China big data technology and the Applied Industry Alliance, Vice Chairman of the China Society of Mechanical Engineering, Vice Chairman of the Chinese Society of Graphics, and Director of the Engineering Graphics Teaching Steering Committee of the Ministry of Education, Jianrong Tan successively awarded the “Professional Individual of the Ministry of Science and Technology Fifteen 863”, “Eleventh Five-Year of the Ministry of Science and Technology” National Science and Technology Plan Executive Outstanding Contribution Award, ''National Excellent Science and Technology Worker'' and other honors and titles.
He Mainly engaged in data modeling and virtual reality, digital design and intelligent manufacturing research, won the second prize of the National Science and Technology Progress Award, 7 provincial and ministerial level scientific and technological progress first prize, the teaching achievement won the national outstanding teaching achievement award 3 Among them, 1 first prize and 2 second prize. Obtained 56 registration rights for invention patents and software works.
珞珈讲坛第283讲
时 间：2019年1月9日（周三）9:30
地 点：武汉大学樱顶老图书馆
主讲人：James Fraser Stoddart教授 诺贝尔化学奖获得者
题 目：My Journey to Stockholm
主讲人简介：
詹姆斯·弗雷泽·司徒塔特教授于1966年获得爱丁堡大学博士学位，现任美国西北大学教授。是有机超分子化学和纳米科学领域最杰出的科学家之一，迄今已在《Nature》、《Science》、《Nature Nanotechnology》、《Nature Chemistry》等杂志上发表1000余篇学术论文，h-index = 124，科学引文次数世界排名第三。1994年当选英国皇家科学院院士，1999年当选德国自然科学院院士，2006年当选荷兰皇家艺术与科学院外籍院士，同年被英国皇室伊丽莎白二世授予勋爵爵位，2007年因其在分子机器领域的杰出和开创性工作获得了爱因斯坦科学奖。2012年当选美国人文与科学院院士，2014年当选美国科学院院士，2016年获得诺贝尔化学奖， 并入选“外教中国”十大年度人物，2017年当选为中国科学院外籍院士并获2017年度中国政府友谊奖。在司徒塔特教授从事科学研究的40余年期间，他做了1000余场学术邀请报告，成功培养了超过400名博士和博士后，其中80余人任职于国际著名大学。
司徒塔特教授的研究领域主要为超分子化学和分子机器。他基于分子机械互锁结构创造性地发展出了一种全新的人工合成分子机器，提出了有别于传统化学价键理论的机械键概念，为化学领域的进一步拓展做出了里程碑式的贡献。他与索维奇共同开拓的基于非共价键作用的模板合成法大大提高了机械互锁分子机器的合成效率。他合成出由热能驱动的分子机器原型—分子梭，以及可以对外部刺激做出响应的分子开关等。通过构筑能量棘轮，他巧妙地设计合成了可以对外做功的真正意义上的分子机器—分子泵。同时，司徒塔特将分子机器的概念拓展到了各种应用领域，比如基于分子尺寸的高密度存储器件等。此外，他不仅在分子级别上实现了如奥林匹克环、博罗米恩环等具有拓扑结构的复杂体系，还进一步将超分子化学与拓扑学进行有机结合，提出了“机械立体化学”的概念，推动了分子拓扑学在化学领域的发展。他和相关科学家的有关分子机器的工作打开了化学领域一扇新的大门，将人类“机械文明”带入到了一个全新的分子维度。
Brief Introduction of Professor James Fraser Stoddart
Sir James Fraser Stoddart got his PhD at Edinburgh University in 1966 and is Board of Trustees Professor of Chemistry. Sir Fraser is one of the outstanding scientists in area of supramolecular chemistry and nanotechnology. Sir Fraser has published more than 1000 peer reviewed papers on the journal including Nature, Science, Nature Nanotechnology, and Nature Chemistry. As of 2016 Sir Stoddart has an h-index of 124. For the period from January 1997 to 31 August 2007, he was ranked by the Institute for Scientific Information as the third most cited chemist. Sir Fraser was elected as a Fellow of the Royal Society of London in 1994, the Fellowship of Natural Sciences (Leopoldina) of Germany in 1999, and the Foreign membership of Science Division of the Royal Netherlands Academy of Arts and Sciences in 2006. Stoddart was appointed a Knight Bachelor in the New Year's Honours December 2006, by Queen Elizabeth II. In 2007, he received the Albert Einstein World Award of Science in recognition for his outstanding and pioneering work in molecular machines. He was also elected the Fellowship of American Academy of Arts and Sciences in 2012 and the Membership of National Academy of Science, USA in 2014. In 2016 Sir Fraser shared the Nobel Prize in Chemistry together with Ben Feringa and Jean-Pierre Sauvage for the design and synthesis of molecular machines. He was also elected as one of the “International Educator in China Award” in 2016, the Foreign membership of the Chinese Academy of Science in 2017, and one of the winners of “Chinese Government Friendship Award” in 2017. He has given >1,000 plenary/invited lectures. During 45 years, >400 PhD and postdoctoral students have passed through his laboratories and been inspired by his imagination and creativity, and >80 have subsequently embarked upon successful independent academic careers.
Sir Fraser works in the areas of mechanostereochemistry and molecular machine. He creatively developed a new synthetic molecular machine based on molecular mechanical interlocking structure, and put forward the mechanical bond concept different from the traditional chemical valence bond theory, making a landmark contribution to the further development of the field of chemistry. He and Sauvage developed the template synthesis method based on non-covalent bonding, which greatly improved the synthetic efficiency of mechanical interlocking molecular machines. He created prototypes of thermally driven molecular machines, molecular shuttles, and molecular switches that respond to external stimuli. By building an energy ratchet, he designed and synthesized a true molecular machine that could do work on the outside system -- a molecular pump. Sir Fraser also extended the concept of molecular machines to a variety of applications, such as high-density storage devices based on molecular size. In addition, he not only realized the complex topological systems such as the Olympic ring and Borromean ring at the molecular level, but also organically combined supramolecular chemistry and topology, and proposed the concept of "mechanical stereochemistry", which promoted the development of molecular topology in the field of chemistry. His work on molecular machines with relevant scientists opened a new door in the field of chemistry and brought human to the "mechanical civilization" at molecular dimensions.
珞珈讲坛第284讲
时 间：2019年1月9日（周三）15 ：00
地 点：武汉大学樱顶老图书馆
主讲人：邵峰教授 中国科学院院士
题 目：Innate immunity to cytosolic bacteria: pyroptosis and beyond
主讲人简介：
邵峰博士1996年毕业于北京大学技术物理系，1999年于中科院生物物理所获得硕士学位，2003年美国密西根大学生物化学系获得博士学位，现为北京生命科学研究所资深研究员、科研副所长。
邵峰博士长期研究病原细菌和宿主相互作用机理，在致病菌毒力机制以及抗细菌天然免疫方向均取得系列重要原创性发现：包括发现细菌内毒素（LPS）、鞭毛以及病原菌三型分泌系统的胞内天然免疫受体（组装形成炎症小体复合物），进而揭示和阐明了这些受体下游的炎性caspase通过剪切活化Gasdermin D（GSDMD）蛋白诱导细胞焦亡的确切分子机制；这些发现为败血症药物和细菌疫苗的研发提供了新的理论基础，其中有关Gasdermin家族蛋白的鉴定和机制的阐述也将细胞焦亡的概念重新定义为由Gasdermin家族介导的细胞程序性坏死。邵峰博士已发表学术论文70多篇，总引用9,000次，2005年回国后以通讯作者在《自然》、《科学》和《细胞》三大杂志发表研究论文13篇；获得多项国际和国内重要奖项，包括周光召杰出青年基础科学奖、HHMI国际青年科学家奖、国际蛋白质学会鄂文西格青年科学家奖、吴阶平-保罗杨森基础医学奖以及何梁何利基金科学与技术奖等，2015年当选为中科院院士和EMBO的外籍成员，2016年当选为美国微生物学院院士。
Brief Introduction of Professor Feng Shao
Dr. Feng Shao graduated from the School of Physics at Peking University and received his bachelor degree in Applied Chemistry in 1996, received his master degree in Molecular Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing in 1999, and received his Ph.D. in Biological Chemistry, University of Michigan Medical School, USA. Currently, he is a senior investigator and deputy director at National Institute of Biological Sciences, Beijing.
Dr. Feng Shao’s laboratory is interested in studying the interaction mechanisms of Bacterial pathogens and the host. His laboratory work has led to several a series of important and original discoveries in the pathogenic virulence mechanism and anti-bacterial natural immunity. For instance, the laboratory found that bacterial endotoxin (LPS), flagella and intracellular secretion system of pathogens innate immune receptors (assembled to form inflammatory corpuscle complexes), which in turn reveals and elucidates the exact molecular mechanisms of which inflammatory caspase downstream of these receptors induces cell pyroptosis by shearing and activating Gasdermin D (GSDMD) proteins; these findings provide a new theoretical basis for the development of the sepsis pharmaceuticals and bacterial vaccines, and the elaboration of the identification and mechanism of the Gasdermin family also redefines the concept of cell pyroptosis into a programmed necrosis mediated by the Gasdermin family. Dr. Shao Feng has published more than 70 academic papers, which have been quoted by 9,000 times in total. After returning to China in 2005, he published 13 research papers in the three major journals of Nature, Science and Cell. He won several international and domestic important awards include Zhou Guangzhao Outstanding Youth Foundation Science Award, HHMI International Young Scientist Award, International Protein Society Evansig Young Scientist Award, Wu Jieping & Paul Yangsen Basic Medicine Award, and the He Liang & He Li Fund Science and Technology Award. He was elected as an academician of the Chinese Academy of Sciences and a foreign member of EMBO in 2015, and was elected as the fellow of the College of Microbiology of United States in 2016.
